Human Gasdermin like (GSDMB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GSDMB
Locus ID	55876
Kit Components	GA111035G1, Gasdermin like gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111035G2, Gasdermin like gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111035G3, Gasdermin like gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042471, NM_001165958, NM_001165959, NM_018530, NM_001369402
Synonyms	GSDML; PP4052; PRO2521
Summary	This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016]

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