Human ANKH activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ANKH
Locus ID	56172
Kit Components	GA111152G1, ANKH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111152G2, ANKH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111152G3, ANKH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019847, NM_054027
Synonyms	ANK; CCAL2; CMDJ; CPPDD; HANK; MANK
Summary	This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008]

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