Human SAR1 (SAR1A) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SAR1A
Locus ID	56681
Kit Components	GA111221G1, SAR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111221G2, SAR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111221G3, SAR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142648, NM_020150
Synonyms	masra2; SAR1; Sara; SARA1
Summary	Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).[UniProtKB/Swiss-Prot Function]

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