Human TCIM activation kit by CRISPRa
CAT#: GA111245
TCIM CRISPRa kit - CRISPR gene activation of human transcriptional and immune response regulator
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | TCIM |
Locus ID | 56892 |
Kit Components | GA111245G1, TCIM gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111245G2, TCIM gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111245G3, TCIM gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_020130 |
Synonyms | TC-1; TC1 |
Summary | This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN404798 | C8orf4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |