Human MCCC1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MCCC1
Locus ID	56922
Kit Components	GA111272G1, MCCC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111272G2, MCCC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111272G3, MCCC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001293273, NM_020166, NR_120639, NR_120640, NM_001363880
Synonyms	MCC-B; MCCA
Summary	This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq, Jul 2008]

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