Human CDC42SE2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CDC42SE2
Locus ID	56990
Kit Components	GA111322G1, CDC42SE2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111322G2, CDC42SE2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111322G3, CDC42SE2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001038702, NM_020240
Synonyms	SPEC2
Summary	Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.[UniProtKB/Swiss-Prot Function]

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