Human Zinc finger MIZ domain containing protein 1 (ZMIZ1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ZMIZ1
Locus ID	57178
Kit Components	GA111428G1, Zinc finger MIZ domain containing protein 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111428G2, Zinc finger MIZ domain containing protein 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111428G3, Zinc finger MIZ domain containing protein 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020338
Synonyms	hZIMP10; MIZ; RAI17; TRAFIP10; ZIMP10
Summary	This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]

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