Human SCYL1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SCYL1
Locus ID	57410
Kit Components	GA111487G1, SCYL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111487G2, SCYL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111487G3, SCYL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001048218, NM_020680
Synonyms	GKLP; HT019; NKTL; NTKL; P105; TAPK; TEIF; TRAP
Summary	This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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