Human KLHDC5 (KLHL42) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLHL42
Locus ID	57542
Kit Components	GA111575G1, KLHDC5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111575G2, KLHDC5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111575G3, KLHDC5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020782
Synonyms	Ctb9; KLHDC5
Summary	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis.[UniProtKB/Swiss-Prot Function]

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