Human KIAA1530 (UVSSA) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UVSSA
Locus ID	57654
Kit Components	GA111661G1, KIAA1530 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111661G2, KIAA1530 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111661G3, KIAA1530 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001317934, NM_001317935, NM_020894
Synonyms	KIAA1530; UVSS3
Summary	The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in this gene can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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