Human GBA3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GBA3
Locus ID	57733
Kit Components	GA111721G1, GBA3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111721G2, GBA3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111721G3, GBA3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001128432, NM_001277225, NM_020973, NR_102355, NR_102356, NR_102357
Synonyms	CBG; CBGL1; GLUC; KLRP
Summary	The protein encoded by this gene is an enzyme that can hydrolyze several types of glycosides. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals, as represented by the reference genome allele, contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2013]

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