Human RB associated KRAB repressor (RBAK) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RBAK
Locus ID	57786
Kit Components	GA111725G1, RB associated KRAB repressor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111725G2, RB associated KRAB repressor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111725G3, RB associated KRAB repressor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001204456, NM_021163
Synonyms	ZNF769
Summary	This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]

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