Human EPS15R (EPS15L1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EPS15L1
Locus ID	58513
Kit Components	GA111793G1, EPS15R gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111793G2, EPS15R gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111793G3, EPS15R gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001258374, NM_001258375, NM_001258376, NM_021235, NR_047665, NR_047666
Synonyms	EPS15R
Summary	Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.[UniProtKB/Swiss-Prot Function]

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