Human TGF beta induced factor 2 (TGIF2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TGIF2
Locus ID	60436
Kit Components	GA111847G1, TGF beta induced factor 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111847G2, TGF beta induced factor 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111847G3, TGF beta induced factor 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199513, NM_001199514, NM_001199515, NM_021809
Summary	The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010]

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