Human XPNPEP3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	XPNPEP3
Locus ID	63929
Kit Components	GA111922G1, XPNPEP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111922G2, XPNPEP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111922G3, XPNPEP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001204827, NM_022098
Synonyms	APP3; ICP55; NPHPL1
Summary	The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.[provided by RefSeq, Mar 2011]

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