Human KIF13A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KIF13A
Locus ID	63971
Kit Components	GA111939G1, KIF13A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA111939G2, KIF13A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA111939G3, KIF13A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001105566, NM_001105567, NM_001105568, NM_001243423, NM_022113
Synonyms	bA500C11.2; RBKIN
Summary	This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

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