Human ERAP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERAP2
Locus ID	64167
Kit Components	GA112002G1, ERAP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112002G2, ERAP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112002G3, ERAP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001130140, NM_001329229, NM_001329233, NM_022350, NR_137637
Synonyms	L-RAP; LRAP
Summary	This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016]

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