Human FNDC4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FNDC4
Locus ID	64838
Kit Components	GA112165G1, FNDC4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112165G2, FNDC4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112165G3, FNDC4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_022823
Synonyms	FRCP1
Summary	Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.[UniProtKB/Swiss-Prot Function]

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