Human RAPH1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RAPH1
Locus ID	65059
Kit Components	GA112226G1, RAPH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112226G2, RAPH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112226G3, RAPH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025252, NM_203365, NM_213589, NM_001329728
Synonyms	LPD, RMO1, PREL2, ALS2CR9, ALS2CR18, KIAA1681, RalGDS/AF-6
Summary	This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

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