Human CUEDC2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CUEDC2
Locus ID	79004
Kit Components	GA112304G1, CUEDC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112304G2, CUEDC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112304G3, CUEDC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_024040
Synonyms	bA18I14.5; C10orf66
Summary	Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.[UniProtKB/Swiss-Prot Function]

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