Human TUG (ASPSCR1) activation kit by CRISPRa

CAT#: GA112340

ASPSCR1 CRISPRa kit - CRISPR gene activation of human ASPSCR1 tether for SLC2A4, UBX domain containing



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol ASPSCR1
Locus ID 79058
Kit Components

GA112340G1, TUG gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112340G2, TUG gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112340G3, TUG gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001251888, NM_001330528, NM_024083, NR_045351
Synonyms ASPCR1; ASPL; ASPS; RCC17; TUG; UBXD9; UBXN9
Summary The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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