Human CARD14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CARD14
Locus ID	79092
Kit Components	GA112364G1, CARD14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112364G2, CARD14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112364G3, CARD14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001257970, NM_024110, NM_052819, NR_047566, NM_001366385
Synonyms	BIMP2; CARMA2; PRP; PSORS2; PSS1
Summary	This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]

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