Human FKRP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FKRP
Locus ID	79147
Kit Components	GA112384G1, FKRP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112384G2, FKRP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112384G3, FKRP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039885, NM_024301
Synonyms	LGMD2I; MDC1C; MDDGA5; MDDGB5; MDDGC5
Summary	This gene encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in this gene have been associated with congenital muscular dystrophy, cognitive disability, and cerebellar cysts. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]

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