Human L2HGDH activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	L2HGDH
Locus ID	79944
Kit Components	GA112746G1, L2HGDH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112746G2, L2HGDH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112746G3, L2HGDH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_024884
Synonyms	C14orf160; L2HGA
Summary	This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe cognitive disability. [provided by RefSeq, Jul 2008]

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