Human C13orf18 (RUBCNL) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RUBCNL
Locus ID	80183
Kit Components	GA112855G1, C13orf18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112855G2, C13orf18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112855G3, C13orf18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286761, NM_001286762, NM_001286763, NM_001286764, NM_001286765, NM_001286766, NM_025113, NM_001349772
Synonyms	C13orf18; KIAA0226L
Summary	This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients. [provided by RefSeq, Mar 2017]

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