Human PRRT1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRRT1
Locus ID	80863
Kit Components	GA113005G1, PRRT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113005G2, PRRT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113005G3, PRRT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_030651, NM_001363780
Synonyms	C6orf31; DSPD1; IFITMD7; NG5
Summary	Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function. Regulates basal AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses. Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression.[UniProtKB/Swiss-Prot Function]

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