Human PLA2G12A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLA2G12A
Locus ID	81579
Kit Components	GA113080G1, PLA2G12A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113080G2, PLA2G12A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113080G3, PLA2G12A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_030821
Synonyms	GXII; PLA2G12; ROSSY
Summary	Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).[supplied by OMIM, Mar 2008]

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