Human TSPAN14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TSPAN14
Locus ID	81619
Kit Components	GA113095G1, TSPAN14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113095G2, TSPAN14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113095G3, TSPAN14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001128309, NM_030927, NM_001351266, NM_001351267, NM_001351268, NM_001351269, NM_001351270, NM_001351271, NM_001351272
Synonyms	DC-TM4F2; TM4SF14
Summary	Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26668317, PubMed:23035126, PubMed:26686862). Negatively regulates ADAM10-mediated cleavage of GP6 (By similarity). Promotes ADAM10-mediated cleavage of CDH5 (By similarity).[UniProtKB/Swiss-Prot Function]

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