Human DYNLRB1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DYNLRB1
Locus ID	83658
Kit Components	GA113227G1, DYNLRB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113227G2, DYNLRB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113227G3, DYNLRB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001281727, NM_001281728, NM_001281729, NM_014183, NM_177953, NM_177954, NR_104032, NM_001319157
Synonyms	BITH; BLP; DNCL2A; DNLC2A; ROBLD1
Summary	This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]

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