Human SETDB2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SETDB2
Locus ID	83852
Kit Components	GA113273G1, SETDB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113273G2, SETDB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113273G3, SETDB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001160308, NM_031915, NM_001320699
Synonyms	C13orf4; CLLD8; CLLL8; KMT1F
Summary	This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

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