Human WDR54 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	WDR54
Locus ID	84058
Kit Components	GA113342G1, WDR54 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113342G2, WDR54 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113342G3, WDR54 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001320823, NM_001320824, NM_001320825, NM_032118
Summary	When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation.[UniProtKB/Swiss-Prot Function]

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