Human DARPP32 (PPP1R1B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PPP1R1B
Locus ID	84152
Kit Components	GA113395G1, DARPP32 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113395G2, DARPP32 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113395G3, DARPP32 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001242464, NM_032192, NM_181505
Synonyms	DARPP-32; DARPP32
Summary	This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

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