Human C12orf62 (COX14) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	COX14
Locus ID	84987
Kit Components	GA113818G1, C12orf62 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113818G2, C12orf62 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113818G3, C12orf62 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001257133, NM_001257134, NM_032901
Synonyms	C12orf62
Summary	This gene encodes a small single-pass transmembrane protein that localizes to mitochondria. This protein may play a role in coordinating the early steps of cytochrome c oxidase (COX; also known as complex IV) subunit assembly and, in particular, the synthesis and assembly of the COX I subunit of the holoenzyme. Mutations in this gene have been associated with mitochondrial complex IV deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

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