Human HPS4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HPS4
Locus ID	89781
Kit Components	GA113927G1, HPS4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113927G2, HPS4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113927G3, HPS4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_022081, NM_152840, NM_152841, NM_152842, NM_152843, NR_073135, NR_073136, NM_001349896, NM_001349898, NM_001349899, NM_001349900, NM_001349901, NM_001349902, NM_001349903, NM_001349904, NM_001349905, NR_146311, NR_146312, NR_146313, NR_146314, NR_146315, NR_146316
Synonyms	LE
Summary	This gene encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

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