Human PRMT10 (PRMT9) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRMT9
Locus ID	90826
Kit Components	GA114061G1, PRMT10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114061G2, PRMT10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114061G3, PRMT10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001304458, NM_138364, NM_001350141, NM_001350142, NM_001350143, NM_001350144
Synonyms	PRMT10
Summary	This gene encodes a type II methyltransferase. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to the guanidino nitrogen atoms of arginine. The protein encoded by this gene methylates spliceosome associated protein 145 to regulate alternative splicing and acts as a modulator of small nuclear ribonucleoprotein maturation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2017]

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