Human CABLES1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CABLES1
Locus ID	91768
Kit Components	GA114153G1, CABLES1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114153G2, CABLES1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114153G3, CABLES1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001100619, NM_001256438, NM_138375, NR_023359
Synonyms	CABL1; CABLES; HsT2563; IK3-1
Summary	This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

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