Human NAF1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NAF1
Locus ID	92345
Kit Components	GA114209G1, NAF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114209G2, NAF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114209G3, NAF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001128931, NM_138386
Synonyms	nuclear assembly factor 1 homolog; nuclear assembly factor 1 homolog (S. cerevisiae)
Summary	RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.[UniProtKB/Swiss-Prot Function]

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