Human c20orf72 (MGME1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MGME1
Locus ID	92667
Kit Components	GA114229G1, c20orf72 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114229G2, c20orf72 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114229G3, c20orf72 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001310338, NM_001310339, NM_052865, NM_001363738
Synonyms	bA504H3.4; C20orf72; DDK1; MTDPS11
Summary	The protein encoded by this gene is a nuclear-encoded mitochondrial protein necessary for the maintenance of mitochondrial genome synthesis. The encoded protein is a RecB-type exonuclease and primarily cleaves single-stranded DNA. Defects in this gene have been associated with mitochondrial DNA depletion syndrome-11. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]

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