Human HNRPLL (HNRNPLL) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HNRNPLL
Locus ID	92906
Kit Components	GA114248G1, HNRPLL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114248G2, HNRPLL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114248G3, HNRPLL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142650, NM_138394
Synonyms	HNRPLL; SRRF
Summary	HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]

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