Human NAPRT1 (NAPRT) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NAPRT
Locus ID	93100
Kit Components	GA114263G1, NAPRT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114263G2, NAPRT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114263G3, NAPRT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001286829, NM_145201, NM_001363146, NM_001363145
Synonyms	NAPRT1; PP3856
Summary	Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008]

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