Human IL17F activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IL17F
Locus ID	112744
Kit Components	GA114365G1, IL17F gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114365G2, IL17F gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114365G3, IL17F gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_052872, NM_172343
Synonyms	CANDF6; IL-17F; ML-1; ML1
Summary	The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]

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