Human HENMT1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HENMT1
Locus ID	113802
Kit Components	GA114419G1, HENMT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114419G2, HENMT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114419G3, HENMT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001102592, NM_144584
Synonyms	C1orf59; HEN1
Summary	Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.[UniProtKB/Swiss-Prot Function]

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