Human LACTB activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LACTB
Locus ID	114294
Kit Components	GA114432G1, LACTB gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114432G2, LACTB gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114432G3, LACTB gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001288585, NM_032857, NM_171846
Synonyms	G24; MRPL56
Summary	This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic function. Increased expression of the related mouse gene was found to be associated with obesity. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Dec 2013]

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