Human GRIN3A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GRIN3A
Locus ID	116443
Kit Components	GA114593G1, GRIN3A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114593G2, GRIN3A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114593G3, GRIN3A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_133445
Synonyms	GluN3A; NMDAR-L; NR3A
Summary	This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008]

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