Human UBE2J2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UBE2J2
Locus ID	118424
Kit Components	GA114654G1, UBE2J2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114654G2, UBE2J2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114654G3, UBE2J2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018618, NM_058167, NM_194315, NM_194316, NM_194457, NM_194458
Synonyms	NCUBE-2; NCUBE2; PRO2121
Summary	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

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