Human PDZD8 activation kit by CRISPRa
CAT#: GA114680
PDZD8 CRISPRa kit - CRISPR gene activation of human PDZ domain containing 8
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | PDZD8 |
Locus ID | 118987 |
Kit Components | GA114680G1, PDZD8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114680G2, PDZD8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114680G3, PDZD8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_173791 |
Synonyms | PDZK8 |
Summary | Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes (PubMed:29097544). PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca(2+) transfer (PubMed:29097544). In neurons, involved in the regulation of dendritic Ca(2+) dynamics by regulating mitochondrial Ca(2+) uptake in neurons (PubMed:29097544). Plays an indirect role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987). May inhibit herpes simplex virus 1 infection at an early stage (PubMed:21549406).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN405601 | PDZD8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |