Human PDZD8 activation kit by CRISPRa

CAT#: GA114680

PDZD8 CRISPRa kit - CRISPR gene activation of human PDZ domain containing 8



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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PDZD8 Antibody - C-terminal region
    • 100 ul

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PDZD8 (Myc-DDK-tagged)-Human PDZ domain containing 8 (PDZD8)
    • 10 ug

CNY 12048.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol PDZD8
Locus ID 118987
Kit Components

GA114680G1, PDZD8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114680G2, PDZD8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114680G3, PDZD8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_173791
Synonyms PDZK8
Summary Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes (PubMed:29097544). PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca(2+) transfer (PubMed:29097544). In neurons, involved in the regulation of dendritic Ca(2+) dynamics by regulating mitochondrial Ca(2+) uptake in neurons (PubMed:29097544). Plays an indirect role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987). May inhibit herpes simplex virus 1 infection at an early stage (PubMed:21549406).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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