Human JDP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	JDP2
Locus ID	122953
Kit Components	GA114793G1, JDP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114793G2, JDP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114793G3, JDP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001135047, NM_001135048, NM_001135049, NM_130469
Synonyms	JUNDM2
Summary	Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.[UniProtKB/Swiss-Prot Function]

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