Human KIAA1970 (EARS2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EARS2
Locus ID	124454
Kit Components	GA114841G1, KIAA1970 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114841G2, KIAA1970 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114841G3, KIAA1970 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001083614, NM_001308211, NM_133451, NR_003501
Synonyms	COXPD12; gluRS; MSE1
Summary	This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]

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