Human TBC1D20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TBC1D20
Locus ID	128637
Kit Components	GA115054G1, TBC1D20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115054G2, TBC1D20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115054G3, TBC1D20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_144628, NR_111901
Synonyms	C20orf140; WARBM4
Summary	This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replication. Depletion of this protein inhibits replication of the virus and HCV infection. Mutations in this gene are associated with Warburg micro syndrome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

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