Human RFTN2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RFTN2
Locus ID	130132
Kit Components	GA115105G1, RFTN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115105G2, RFTN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115105G3, RFTN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_144629
Synonyms	C2orf11; Raftlin-2
Summary	Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling.[UniProtKB/Swiss-Prot Function]

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